For the complex layout of large civil transport airports with multiple terminals and aprons, to scientifically determine the usage pattern of the multi-terminal area, based on the construction of multi-terminal area operation influence factors set, the AISM model is improved by using the Fuzzy Theory, The horizontal intercept distribution is in-depth analyzed by the fuzzy reachable matrix, and then the confrontation hierarchy model of multi-terminal area operation influence factors is obtained. Finally, the correlation and logic between the factors are analyzed by the topology diagram of the adversarial hierarchy and the fuzzy driver-dependency diagram, and the long-term planning of one of the trunk airports of the Guangdong-Hong Kong-Macao Greater Bay Area is used as an example to verify. The results show that the annual airline passenger traffic and the number of airline peak hour passengers have higher driving force and weaker dependence; the airline space allocation and utilization strategy and the accessibility of the decentralized inter-terminal MRT system have lower driving force and higher dependence. Combining the surface, intermediate, and deep influencing factors revealed by the confrontation hierarchy topology diagram, it is clear that annual airline passenger traffic and peak hour passenger count are the most root and critical design influencing factors of zonal operation.