In order to explore the impact of different evaluation index systems on the evaluation results of debris flow susceptibility. Control group index system including vegetation coverage, stratum lithology, topographic relief, surface roughness, gully density, distance to fault and PGA. The ratio index of potential instability area to the catchment area is obtained through slope stability analysis. Test group index system including topographic relief, surface roughness, gully density, distance to fault, PGA and ratio index of potential instability area to the catchment area. The certainty factor method is used to assessment the susceptibility of debris flow, and the debris flow susceptibility are set as high, relatively high, middle, relatively low and low on Anning River. The results shows that the frequency ratio of high and relatively high susceptibility of test group and control group index system on Anning River are 88.17% and 85.88%, respectively. The two evaluation index systems objectively and effectively evaluate the susceptibility of debris flow. The area under curve(AUC) of test group index system is 0.767. Test group index system can improve evaluation 1.99% compared to control group index system. The evaluation result of debris flow susceptibility by adding slope stability analysis factor in the debris flow susceptibility evaluation index system is better than that only considering disaster pregnant environmental factors. It provides a new idea for improving the evaluation results of debris flow susceptibility.