In order to solve the problem of insufficient consideration,the influence of existing integrated energy system operation optimization research on building cooling load (mostly replacing air-conditioning cooling load with typical daily load or forecasting load), firstly, a park in Beijing is modeled and loaded by EnergyPlus software, and then optimized with economy as the objective, based on typical equipment model and Park Power supply and load. , Constraint model is established for the balance of supply and demand of cooling load, and operation optimization model for air-conditioning period of multi-energy coupling integrated energy system is established. Using Yalmip modeling and programming and Cplex solution, the operation optimization scheme of integrated energy system during air conditioning period under different load conditions is obtained, and its uniformity and difference are analyzed. The results show that the optimization model constructed in this paper can optimize the operation of multi-energy coupling integrated energy system. Operational optimization schemes under different building cooling load conditions are quite different. Operating optimization schemes under different load conditions have certain regularity. It is concluded that the influence of cold load should be considered in the study of operation optimization of integrated energy system. The regular operation optimization scheme proposed in this paper provides a basis for improving operation economy of integrated energy system.