By designing a priority queuing mechanism with limited capacity, an efficiency evaluation model for the vehicle-mounted hydrogen safety monitoring system is proposed under the condition of monitoring process disturbance. When the priority of demand monitoring is related to urgency, the high-level signals of the monitoring system are processed first to improve the safety and effectiveness of the monitoring system. Taking into account the potential impact of the reliability factors of the vehicle-mounted hydrogen safety monitoring device on the efficiency of the safety monitoring system, a sensitivity analysis of the system failure loss and queuing cost of the monitor reliability under different probability conditions is carried out to provide a vehicle-mounted hydrogen safety monitoring system. It is concluded that technical support and control strategy reference can be provided.