In order to better monitor and grasp the land subsidence of the Shenzhen reclamation area after the reclamation project is completed, Sentinel-1A image and Time-series synthetic radar interferometry method was used to investigate the land deformation in Shenzhen reclamation area from 2016 to 2019. The results show that The land speed change rate of the Shenzhen reclamation area is -19.85 ~ 15.60 mm/year, the land subsidence in Baoan District in eastern Shenzhen and Futian District in western China is relatively stable, a large area of land subsidence was detected in Nanshan District. The comparative analysis with the average annual rainfall shows that there are obvious seasonal changes in land subsidence in Nanshan District. The deformation point target close to the coast is obviously affected by rainfall than other points, and there is a clear correlation with the thickness of the sedimentary layer in Shenzhen.