Sangezhuang uplift is located in the west edge of Chaiwopu basin at the south flank of the Bogda Mountain, sandwiched between Bogda structural belt and Yilianhabilga structural belt. The structural evolution of sangezhuang uplift plays an key role in the study of regional structure evolution and the initial uplift of Bogda Mountain. Combined on the two-dimensional seismic data interpretation, evolution profile production and previous research results, the structural characteristics and evolution process of sangezhuang uplift are revealed. It is considered that the formation of sangezhuang uplift has experienced three multi-stage tectonic uplift, which is highly consistent with previous studies on Bogda mountain. Controlled by the tectonic movement, the sangezhuang uplift formed three obvious angular unconformities, including the unconformity at the bottom of Triassic, the unconformity at the bottom of Jurassic and the unconformity at the bottom of Paleogene. In the Late Permian, the first uplift of Bogda mountain resulted in the subsequent uplift of sangezhuang, which resulted in the unconformity of the bottom of Triassic. Under the influence of Indosinian movement, Bogda area suffered a strong compression movement during Late Triassic, and the angle unconformity between Triassic and Jurassic was shown in sangezhuang uplift. During the Cenozoic, the continuous uplift of Bogda mountain and North Tianshan Mountain resulted in the compression and subsidence of the southern part of sangezhuang uplift, meantwhile the Cenozoic sedimentary covered the western part of Bogda mountain.