The first shale gas horizontal well Liye 1HF deployed in the Lishu faulted depression has technical problems such as high risk of wellbore instability, low rate of penetration, difficult in cementing construction, and difficulty in wellbore trajectory control. In the construction process of the Liye 1HF well, the oil-based drilling fluid, rotary-steering geo-steering, double-condensation double-density cement slurry and other technologies were comprehensively applied, and the optimization of the drill bit and the drilling tool combination optimization were carried out. During the construction process, the wellbore was stable and the wellbore trajectory was smooth. The horizontal section had a total footage of 1020m, the reservoir drilling rate was 92.7%, and the cementing quality was excellent. The well achieves safe and efficient drilling. The actual drilling cycle is 22.56 days, which is shortened by 14.94 days compared with the designed drilling cycle, and the average rate of penetration is 7.98m/h, which is 82.19% higher than the design. The good construction effect of the well has positive guidance and reference for the subsequent construction of shale gas horizontal wells in the Lishu faulted depression.