In order to evaluate the damage effect of shock wave after the brick partition wall was damaged, based on experimental results of the shock wave effect after the failure of the brick partition wall caused by the explosion in front of brick partition wall and combining with dimensional analysis, specific engineering algorithms of the leakage shock wave effect were presented, including: the leakage shock wave overpressure peak, the equivalent coefficient of charges compared without brick partition wall and the reduction coefficient of shock wave overpressure with the presence and absence of the brick partition wall, etc. The results showthat the reasonable setting of the brick partition wall can consume most of the energy of the explosion and reflect a certain anti-blast protection.