Based on the two-dimension particle flow code software (PFC2D ), the deformation and failure process of anti-dip layered rock slope is simulated, and effects of rock mass discontinuity parameters (dip angle, thickness and joint shear strength) on its deformation and failure mechanism were taken into account. The numerical simulation results show that the main failure mode of the slope strata is bending deformation and fracture failure. The deformation first occurs at the top of the slope, while the failure starts from the slope foot, and the failure characteristic of this kind of slope is similar to that of cantilever. The rock dip angle has a great impact on the overall failure mode of the anti-dip rock slope. With the increase of the rock dip angle, the integral failure mode of the slope in the later stage gradually changes from sliding mode to toppling mode, and the depth of rock deformation and fracture damage inside the slope body increases gradually. As the thickness of the rock layer increases, the Fracture resistance of the rock mass at the foot of the slope increases, the failure mode develops from fracture failure to shear failure, and the integral failure mode in the later stage of the slope also transitions from sliding mode to toppling mode. The shear strength of joint is also an important factor influencing the slope deformation. The smaller the shear strength at the stratum level, the greater the bending deformation of the slope.