Based on the MOD13QI data of 2000-2016 years (5-10 months), combined with the data of temperature and precipitation at the same time, the linear trend analysis and correlation analysis were used to study the spatial change characteristics of vegetation in the last 16 years in Hami and the relationship with the climatic factors. The results show that:NDVI in Hami city showed an overall upward trend, and the main vegetation types were low coverage vegetation types. During the periods of 2000 - 2008 and 2008 - 2016, the vegetation with extremely low coverage and extremely high coverage decreased first and then increased, while the vegetation with low coverage and high coverage continued to increase, while the vegetation with medium coverage continued to decrease. NDVI has a certain correlation with temperature and precipitation, and NDVI is less affected by the temperature, and is significantly affected by the precipitation.