Aiming at the problem of high CO2 acid gas in Sulige oil and gas field during cementing, through analyzing the corrosion mechanism of CO2 to cement stone, a water-soluble resin(SRSZ) with acid response characteristic is added into cement slurry as anticorrosion agent. The changes of carbonation depth, compressive strength, permeability, pore size distribution and microstructure of hydration products were studied at CO2 environmental maintenance condition. The results show that the water-soluble resin(SRSZ) can effectively inhibit the sharp decline in compressive strength and the increase of permeability after the corrosion. After 35days of CO2 corrosion, the increase rate of corrosion depth of SRSZ cement stone (relative to blank cement stone) is 14.60%, the decline rate of compressive strength is 6.65%, and the permeability decline rate is 9.63%. The total porosity was reduced by 16.31%, the pore size was refined, the harmful pore (>100nm) decreased, and the gel pore (<50nm) increased. The corrosion surface of cement stone forms a continuous distribution membrane materials, which makes the cement stone structure compact, and is beneficial to improve the carbonation resistance of cement stone.