The hazard assessment of debris flow provides an important basis to establish reasonable prevention and control measures of debris flow. The 26 rainfall-induced debris flows along the Aoyitake-Bulunkou section of Karakoram Highway are selected as the study object. Based on field investigation and remote sensing, 8 indicators influencing development of debris flow are selected as the basic evaluation factors, including average slope, engineering geological rock formation, maximum 24h rainfall, average annual temperature, accumulation fan area, distance from the fault zone, gradient, relative height difference. The principal component analysis method is used to carry out evaluation factor screening and determination of the weights, and correlation degree is calculated by the grey system, further a suitable model for debris flow hazard assessment is built. The evaluation results show that rainfall-induced debris flows along the highway are in moderate-high hazard levels, with very high hazard of 11.54% , high hazard of 19.23%, medium hazard of 57.69% and lighthazardof11.54%.Research results are consistent with the actual situation, and show that the evaluation model is feasible. So the evaluation model can provides scientific basis and guidance for debris flow hazard assessment and route alignment along and near KKH.