Chatter marks are prone to produce on the surface of steel strip which results in a bad surface quality and even a bad influence on the steel service. However, due to the complicated mill operation condition, one of present existing problems is that rolling parameters loading ways effects the chatter vibration of roll mill. The paper proposes the Sendzimir twenty-high roll mill coupled dynamic model and analyzes the effect of rolling speed on the rolling mill vibration characteristics in the process of loading. The models are tested by field test, and the empirical studies show that the proposed model is effective and the analysis process is reasonable. And providing a theoretical and practical support for optimizing rolling parameters loading ways, restraining the chatter vibration, and improving the quality of the strip surface and economic benefits.