The shock response law of pressure sensors is obtained by impact experiment. Shock wave and the transient high impact are simultaneously loaded on the sensors in shock tube. The relationship between the peak value of the impact parasitic response of the pressure sensor and the impact acceleration is acquired. Additional the pulse width of the impact parasitic response and the natural frequency are related. Finally the validation test is carried out in the actual explosion field. The results show that the acceleration sensitivity of the pressure sensor is approximately constant and different from the others. The peak value of impact parasitic response of the pressure sensor under transient high impact is related to its acceleration sensitivity. The pulse width is related to the natural frequency of the structure on the measuring point. Reasonable choice of pressure sensors is essential to reduce parasitic output. The natural frequency of the structure on the measuring point should be controlled to make the peak of acceleration away from that of the pressure.