Because the ultra-wide band technology possesses many advantages, such as the good anti-interference effect, high security, and the precise positioning, the ultra-wide technology becomes the primary choice in the wireless positioning technology. Positioning system small size, low power consumption, convenient installation, Algorithm mainly started with the traditional positioning technology, combined with the advantages and disadvantages of various positioning technology, proposes an ultra-wide band wireless hybrid positioning algorithm which is the combination of the TDOA and the TSOA. This algorithm can use few reference nodes, have a high positioning precision and applied in a wide range. The results show that, the hybrid location algorithm of TDOA/TSOA measured the distance at 200 m, the error of the location accuracy is within 40 cm.