Under the reservoir conditions of high temperature and high salinity (82℃, total salinity 10×104mg/L), this paper carried out the effects research of sewage containing polymer on polymer powder and fresh solution preparation. Through indoor simulation method, the results show that: With the increase of residual polymer concentration in sewage, the apparent viscosity of polymer solution is larger, shear resistance is enhanced. When the residual polymer concentration is larger than 600mg/L, the improvement viscosity of polymer powder solution is up to 10%. With the increase of oil and suspended solids, the polymer solution viscosity decrease adversely, particularly impact on powder dissolving when the concentration is over 100mg/L. Sewage has a serious impact on the dissolution property and viscosity of polymer solution, so it is recommended that while the residual polymer in produced water retaining, the contention of oil and suspended solids should be reduced as possible.