In view of the relationship permeability with variable axial pressure and confining pressure of two kinds of coal sample coal containing gas, Using self-developed triaxial seepage test device for hot-fluid-solid coupling of coal and rock containing gas, Carried out experimental study of the relationship between permeability and variable axial pressure and confining pressure. Based on the test results show that:(1) The permeability reduced under axial pressure and confining pressure loading of two different kinds sample, the permeability and axial pressure in line with the negative exponential distribution function about tectonic soft coal samples,the same to the confining pressure；Permeability variation and axial pressure changes in line with straight line of hard coal samples；effect of confining pressure for hard coal permeability characteristics In line with the negative exponential distribution function,fitting parameters are given. (2)Axial compression for soft coal permeability changes affect more than hard coal and hard coal with the law change, confining pressure change for two different coal permeability of influence far greater than the axial compression. The study results provide theoretical basis for evolution permeability under conditions of mining.