Tetraamminecopper(II) sulfate solution was prepared by using Copper(II) sulfate pentahydrate and ammonium hydroxide. And then the tetraamminecopper(II) sulfate powder were prepared from tetraamminecopper(II) sulfate solution and ethanol by reversed precipitation method.The influences of single or compound surfactants，such as dodecyl trimethyl ammonium chloride ,span-80 and Sodium dodecyl sulfate on the sedimentation rate and filtration rate of tetraamminecopper(II) Sulfate were mainly studied.Experimental results indicate，under the conditions of reaction temperature of 25 ℃，the stirring time of 0.5 h，the stirring rate of 600 r/min，and in the presence of surfactant，sedimentation rate and filtration rate of tetraamminecopper(II) Sulfate increased obviously.Appropriate surfactants are Cationic surface active agent and compound surfactants.This study provides a theoretical foundation for improving the sedimentation and filtration performance of tetraamminecopper(II) Sulfate.