Aiming at high temperature heterogeneous reservoir of Shuanghe Oilfield VI Formations, a series of simulation experiments were operated to investigate the chromatograph of components , which include surfactant, polymer, organic alkali and crosslinker, of combined chemical systems through long sand packed artificial models. The results indicate that components separation did exist when ASP system flow through porous media under 95℃.Polymer breakthroughs first, and then comes the alkali, surfactant at last as its adsorption. Moreover, organic alkali can reduce the adsorption of surfactant. Experiments were conducted by using interlayer heterogeneous artificial core models, to evaluate the EOR effect of different slug combinations of combined chemical system. A formula, which has organic alkali ASP system as the main slug with two protection slugs constituted by low degree crosslinking-polymer front and back, was elected as the optimized flooding method, and it can promote recovery efficiency by 24.2% after water flooding.