Casing loads and deformation are mutual influence factors in creep stratum. The analytical solution of creep stratum’s casing loads and deformation in non-uniform stresses is studied in the paper, which is one of the main factors to damage casings. It is very hard to calculate the finally steady casing loads and final casing deformation effected by the creep stratum in non-uniform stresses. The casing is taken as the elastic foundation and the stratum as infinite viscoelastic foundation, and then a Kelvin Model of creep stratum is built to analyze the casing loads in non-uniform stresses in the paper. The distribution rules of creep stratum’s casing loads in non-uniform stresses is perfected and then the analytical solution of casing deformation is got by semi-inverse methods and Laplace transform methods. The distribution of creep stratum’s casing loads and impact factors of casing deformation are studied in non-uniform stresses. The conclusion is valuable to the selection of casing used in creep stratum.