This article describes a new type of structural system in which a high-rise buildings——staggered shear walls structure. In order to analyze the seismic performance of shear wall structure and the frame structure, we designed two physical models of the staggered shear wall structure and the frame structure; then did shaking experiments by using small shaking table in these models; got the dynamic response characteristics of the staggered shear walls structure and the frame structure .The result of the experiment shows: the seismic response of the staggered shear walls structure is smaller than the seismic response of the frame structure. It shows that staggered shear walls structure with better seismic performance than the frame structure.