N,N'-bis(salicylidene)-o-phenylenediamine schiff base was synthesized, and the self-assembled monolayer of schiff base was formed on copper surface. Electrochemical workstation was used to analyze the schiff base films for the copper's corrosion inhibition performance. The corrosion of copper in 1mol/LHCl solution was observed by metallography microscope. The results indicated that self-assmbled monolayer has a corrosion inhibition performance on copper. The self-assembled monolayer inhibition efficiency reached 85.3% in 1mol/LHCl solution. The corrosion inhibition efficiency was related with concentration. The high concentration of self-assembled monolayer on copper corrosion inhibition was significantly better than the low.