The study introduces the technology of making artificial cores by the cementation of quartzite and colophony, the artificial cores can well simulate the aeolotropism, permeability and porosity. Good experiment repeatability is another advantage of this manufacture. The artificial cores can be used for the comparison of development plan comparison and assessment of chemistry agent, which is well used in the field of oil/gas field development and well drilling, at the same time, the character of free shape endows the artificial cores with general applicability.