Abstract:To investigate the therapeutic effect of combined therapy in patients with lubar intervertebral disc protrusion. 620 cases of lubar intervertebral disc protrusion were randomly divided into 2 groups. 400 patients were treated with ozone, 220 patients received epidural administration, and all patients received massage and application of herbs. Therapeutic effect of two groups was compared. After 1 year follow-up, all patients had no complications. Group ozone: excellent 290 cases, good in 50 cases, 40 cases improved, 20 cases ineffective, group epidural: excellent 32 cases, good in 45 cases, 66 cases improved, and 77 cases ineffective. The difference of total effective rate was significant (P<0.05). Ozone was significantly better than epidural group, with a good prospect.