Abstract: Launching of airborne missile is a key technique of reconnaissance and strike integrated UAV. The disturbed motion of the small aircraft caused by missile launching has got considerable concern.With the clearances between the missile and launcher,the multibody model of airborne missile launching from UAV was built and simulated. The response characteristic of reconnaissance and strike integrated UAV to launching of airborne missile was studied. The factors effecting the attitude of missile separation from launcher were analyzed.The conclusion of simulation has provided basis for designing corresponding control system.