In order to clarify the static and dynamic performance of the conventional multi-layer steel frame structure with column base hinges, based on the seismic codes of different countries, the Multi-layer steel frame structure model with different design methods (layer design, column beam joint design) and different values ??of strong column coefficients are established. The static and dynamic analysis was preformed on the model with the second-order nonlinear software CLAP, which focus on the model's failure mechanism, maximum interlayer response and structural member hysteresis curve. The results shows: the strong column coefficient of model is 1.2, the structure forms a local failure mechanism according to the column-beam joint design method, and the overall destruction mechanism of the structure is formed with the layer-by-layer design method; while the strong column coefficient ≥ 1.5, all structure model forms an overall failure mechanism. For the model with strong column coefficient ≤ 1.2, the layer-by-layer design can alleviate the interlayer damage of the steel frame structure. The plastic deformation energy of the column end of each model decreases with the increase of the strong column coefficient, while the plastic deformation energy of the beam end increases with The strong column coefficient increases.