Immature shale oil is an important alternative energy in the 21st century. The exploitation of immature shale oil requires continuous heating of the formation. When the formation temperature rises to about 40℃, oil and gas can be produced. But in the case of long-term high-temperature heating, it will cause deformation damage of completion string and failure of cement ring seal, which will lead to wellbore integrity failure. And it will affect the safe and efficient development of oil and gas resources. Therefore, the finite element analysis software is used to establish the integrity model of the immature shale oil wellbore combination, and the integrity research of the high temperature production well bore is carried out in combination with the strength test of cement. The results show that the formation heating effect can be effectively improved by increasing the heater temperature and gas injection pressure. When the cement temperature is higher than 175℃, the cement sheath fails and the yield strength of casing decreases. The use of thermal stress compensator can eliminate the thermal stress of casing, and ensure the safety and environmental protection production of low mature shale production shaft.