In order to study the effect of Streptomyces silaceus on cucumber growth and Fusarium wilt control, the single factor variance analysis of solid fermentation was used to optimize the solid fermentation conditions of strain 11F (seed age, water ratio, inoculum amount, fermentation substrate). The effect of Streptomyces silaceus spores on the heat resistance and UV resistance was tested under different conditions. The effects of strain 11F on the growth of cucumber and the control of cucumber fusarium wilt were studied by pot experiment in greenhouse. The results showed that the best solid fermentation medium was 80% rice + 10% wheat bran, the best ratio of material to water was 1:0.3, the best seed age was 60 h, and the best inoculation amount was 10%. Chitosan was the most suitable carrier of the fungicide. The greenhouse pot experiment showed that the solid fungicide of strain 11F could promote the growth of cucumber. When the ratio of 11F and vermiculite was 1:100, the plant height, root length, fresh weight and dry weight of cucumber seedlings were significantly higher than those of other treatments. The plant height, root length, fresh weight and dry weight increased by 39%, 33.9%, 35.3% and 40.9%, respectively. The growth of cucumber seedlings was vigorous, the leaves were green, and the growth promoting effect was obvious. The control effect of 11F on fusarium wilt of cucumber was 73.45%, which indicated that 11F could be used in the control of cucumber wilt.