In order to study the relationship between ground stress, microseismic activity and ground pressure evolution in mining activities of metal mines, The time-space distribution characteristics of microseismic activities in mining process were analyzed by using high-precision microseismic monitoring system. Based on the study of the variation characteristics of microseismic activity, microseismic cumulative apparent volume, energy index and other parameters under the same time axis, the temporal and spatial evolution law of microseismic activity in mining process and the distribution of moment magnitude were analyzed, the evolution law and trend of mine ground pressure are revealed. It has been successfully applied in a gold mine project in Inner Mongolia. The research results verify the feasibility of using high-precision microseismic monitoring system to analyze the evolution law of mine ground pressure, which can provide reference for the application of microseismic monitoring system in such projects.