In order to alleviate the contradiction of the increasingly serious urban traffic congestion and the increasing volume of logistics goods. Considering the characteristics of urban distribution with large number of customers, wide range and path with strong alternatives and based on the traditional two-echelon open location-routing problem (2E-OLRP) model, a two-echelon open low carbon location-routing problem model based on path flexibility (2E-OLCLRP-WF) was proposed by taking into account the fuel consumption and CO2 emissions in total cost and the flexibility of path selection in route planning simultaneously. The model was coded and solved by CPLEX. For comparison, the Dijkstra algorithm and CPLEX were used to solve the 2E-OLRP model considering the fuel consumption and CO2 emission cost in the same case (ie 2E-OLCLRP model), and the results of the two models were analyzed. The results indicate that compared with the 2E-OLCLRP model, the 2E-OLCLRP-WF model can save a total cost of 0.20%, of which, saving transportation costs by 5.86% and reducing CO2 emissions by 5.98%. Therefore, in order to save the total cost and reduce the CO2 emissions, logistics companies should consider the path flexibility in urban network distribution adequately. The results can provide reference for the decision-making of urban logistics distribution planning.