In order to study the influence of combinations between different cement pavement interface treatments and binders on the resistance of rutting and lateral slippage of composite pavement under high temperature conditions, two-side-unconstrained Hamburg wheel tracking tests was carried out by using different interlayer treatment measures such as acid corrosion treatment, pellet blasting treatment, grooving and two kinds of bonding materials of rubber asphalt binder and AF-I solvent binder. The high temperature rutting resistance and lateral slippage performance of composite pavement were evaluated. The results show that interlayer treatment measures have obvious effects on rutting and lateral displacement. When the interface has a good tectonic depth, the overall anti-deformation ability is significantly improved. It is better to use cross grooves with relatively higher structural depth, denser texture and smaller groove spacing to prevent rutting deformation and lateral displacement diseases. Compared with the specimens using rubber asphalt as binder for interlayer bonding, the specimens using AF-I solvent binder have better resistance to rutting and lateral slippage. In the slip test using two-side-unconstrained composite plate specimens, with the increase of structural depth, the slip deformation rate shows a downward trend, which means that the ability to resist slip deformation increases. Taking appropriate measures to improve the contact conditions between layers is of great significance to improve the high temperature performance of composite pavement asphalt pavement.