Aiming at the problems of enhanced reservoir homogeneity, severe injection water breakthrough and low oil production after polymer flooding in Bohai B oilfield, through laboratory research and evaluation, three heterogeneous composite systems: FJX-1, FJX-2 and FJX-3, were optimized, and the profile control and profile control performance evaluation, and displacement efficiency analysis of heterogeneous combination flooding in high water cut stage after polymer flooding in offshore oilfield have been carried out. The results show that the plugging efficiency of the three heterogeneous composite systems FJX-1, FJX-2 and FJX-3 are 85.21%, 83.45% and 93.17% respectively, and the plugging performance and viscoelastic performance are better than those of the polymer system. Comparing and analyzing the liquid flow diversion ability of FJX-3 and polymer, after injecting FJX-3, the liquid production fraction ratio of high and low permeability layer decreased from 88:12 to 35:65 after water flooding,indicating that the heterogeneous composite system has obvious plugging effect on high permeability layer.The oil displacement experiment shows that compared with polymer flooding, the enhanced oil recovery values of the three heterogeneous composite systems are 6.32%, 3.59% and 11.84%, respectively. The best combination of profile control and flooding slug is profile control (1500mg/L PL + 1500mg/L JLJ) + profile control and flooding (1500mg/L GN + 300mg/L PPG). The heterogeneous composite system has better profile control and profile control performance. By effective blocking of high permeability layer, the crude oil in the medium and low permeability reservoirs is used, also some crude oil remaining in the reservoir has been displaced. Meanwhile, field tests also show that heterogeneous composite flooding has broad prospects for development in offshore oilfields.