Abstract:This paper proposed a new multi-focus image fusion algorithm based on the combination of NSCT and regional characteristic. Firstly, decomposed each source image into highpass subbands and lowpass subbands by NSCT. Secondly, used different fusion rules in different subbands, where region energy rule was adopted in highpass subbands and region variance rule was adopted in lowpass sbbands. Finally, reconstructed the fused image by inverse transform of NSCT. The experimental results showed that the performance of the proposed algorithm was better than that of the other traditional fusion algorithms, prove that the proposed algorithm is reasonable.