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王波. 衣物柔顺剂对孕鼠和胎鼠的毒性[J]. 科学技术与工程, 2010, (12): .
wang bo.Embryonic toxicity of fabric softeners on pregnant and fetal mice[J].Science Technology and Engineering,2010,(12):.
衣物柔顺剂对孕鼠和胎鼠的毒性
Embryonic toxicity of fabric softeners on pregnant and fetal mice
投稿时间:2010-01-23  修订日期:2010-01-30
DOI:
中文关键词:  孕鼠  衣物柔顺剂  胚胎发育
英文关键词:Fabric softener  Pregnant mice  Embryonic development
基金项目:
  
作者单位
王波 西安文理学院生命科学系
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中文摘要:
      摘要:[目的]首次探讨衣物柔顺剂对孕鼠受孕及其胎鼠的发育的影响。[方法]在孕期,以灌胃的方式给予雌性小鼠不同剂量的衣物柔顺剂稀释液(1000,500,100 mg/kg)。观察孕鼠受孕及胚胎发育情况。[结果]试验期间,小鼠的体重随着衣物柔顺剂剂量增加有降低的趋势。高剂量组、中剂量组的活胎率低于对照组。实验组胎鼠的身长、尾长和体重等发育指标均有显著的降低。[结论]衣物柔顺剂对孕鼠受孕及胎鼠的发育具有明显的毒性。
英文摘要:
      Abstract: Objective To explore the fetation adverse effects of fabric softener on mice firstly. Methods The female mice were administered treated by oral gavage with fabric softeners (100, 500 and 1000 mg/kg) during pregnant periods once a day. Reproductive organ weight, maternal body weight, rate of termination of pregnancy and the number of dead embryos as well as visceral histological damage were evaluated. Results The body weight gains of pregnant mice were gradually decreased with the increasing of the dosages of fabric softeners. The livability of fetus in high-dose and medium dose groups was lower than that in the control group. The mean body weight, average body length, tail length significantly decreased. Conclusion Fabric softener had reproductive toxicity in pregnant and fetal mice.
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